Analytical Project Leader (Scientist / Senior Scientist) (6964), Aarau

Analytical Project Leader (Scientist / Senior Scientist) We are currently looking for an Analytical Project Leader for a 12-month contract based in Basel, Switzerland.

2 days a week home office possible after onboarding.

The Analytical Research&Development department is a key part of Synthetic Molecules Technical Development. It is globally responsible for advancing analytical methodologies, performing in-depth analyses of active pharmaceutical ingredients, and diverse dosage forms, as well as preparing detailed regulatory documentation for submission to health authorities.

In this role, you will join a motivated and experienced team of analytical scientists. You will lead the analytical development of synthetic molecule projects involving small molecules, from early development to commercialization. This role offers a unique opportunity to apply your expertise in a dynamic, fast-paced environment and contribute to the development of life-changing medicines.

Main Responsibilities:

Develop a phase-appropriate control strategy for drug substances and drug products.

Collaborate effectively with stakeholders across various departments.

Coordinate comprehensive analytical activities, which involves generating physical and chemical data for materials, developing/improving and validating analytical test methods or other analytical controls and ensuring thorough documentation, timely delivery and adherence to quality standards.

Coach technicians and junior scientists on project work and serve as a central point of contact for project-related information.

Conduct work in compliance with cGMP where applicable, safety, and regulatory requirements.

Supervise internal laboratory activities and/or testing activities at CLOs/CDMOs.

Plan and document experiments/results independently and prepare for regulatory submissions such as IND and NDA.

Qualifications and Experience:

Relevant working/residency permit or Swiss/EU-Citizenship required.

Highly skilled and experienced Analytical Chemist with a strong background in small molecule analysis.

Master’s or Ph.D. in chemistry, pharmacy, or a related field, with at least three years of professional experience in analytical development of drug substances or drug products for small molecules.

In-depth knowledge of chemistry, including synthesis, purification, and characterization.

Expertise in key analytical techniques such as High-Performance Liquid Chromatography (HPLC), Ultra-Performance Liquid Chromatography (UPLC).

Proven experience in developing and validating ICH-compliant analytical methods.

Proficiency in degradation and stability studies for small molecules, including forced degradation and impurity profiling.

Understanding of key requirements for drug substances and drug product specifications.

Excellent command of the English language.

A strong quality mindset and excellent attention to detail.

Digital savviness to support digital transformation initiatives; familiarity with statistical analysis of analytical data is also advantageous.

Proficiency in German is a nice to have.

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